教师一览Chemical Engineering

胡伟伟

作者:审核化学工程学院 日期:2019年11月14日 14:57点击:[]次

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   胡伟伟,工学博士,讲师。2018年6月毕业于东南大学。任职于淮阴工学院化学工程学院,主要从事抗肿瘤药物的筛选、生物活性分子的作用靶点发现及结构改造等研究,在国外知名期刊发表SCI论文数篇。

主要研究方向:

(1)小分了抗肿瘤药物的设计与合成及作用机制研究

(2)生物活性小分子的作用靶点发现及结构修饰研究

代表论文:

1. Hu, Weiwei, Zhao, Jian; Hua, Wuyang; Gou, Shaohua; "Study on Platinum(IV) Species Containing an Estrogen Receptor Modulator to Reverse Tamoxifen Resistance of Breast Cancer", Metallomics (2018), 10, 346.

2. Hu, Weiwei; Fang, Lei; Hua, Wuyang; Gou, Shaohua, "Biotin-Pt(IV)-Indomethacin Hybrid: A Targeting Anticancer Prodrug Providing Enhanced Cancer Cellular Uptake and Reversing Cisplatin Resistance", Journal of Inorganic Biochemistry (2017), 175, 4757.

3. 1Xu, Zichen; 1Hu, Weiwei; Wang, Zhimei; Gou, Shaohua, "Platinum(IV) prodrugs multiply targeting genomic DNA, histone deacetylases and PARP-1", European Journal of Medicinal Chemistry (2017), 141, 211.

4. Hu, Weiwei; Lyu, Chaojie; Gao, Changzhong; Wu, Kaili; Chen, Lihui; Zhu, Xixi; "Engineered changes in structure and component from solid NiS2/rGO to hollow Ni-P/rGO and the enhanced performance for lithium ion batteries", Energy technology (2019)

5. Liu, Fengfan; Hu, Weiwei; Fang, Lei; Gou, Shaohua, "Synthesis and biological evaluation of water-soluble trans-[bicyclo[2.2.2]octane-7R,8R-diamine]platinum(II) complexes with linear or branched alkoxyacetates as leaving groups", Journal of Coordination Chemistry (2016), 69, 1284.